Schedule 2012
Preseason
| WK | DATE | OPPONENT | |
| 1 | Thu, Aug 9 | at Chicago | W 31-3 |
| 2 | Sat, Aug 18 | Seattle | L 30-10 |
| 3 | Sun, Aug 26 | San Francisco | L 29-24 |
| 4 | Thu, Aug 30 | at Arizona | W 16-13 |
Regular Season
| WK | DATE | OPPONENT | |
| 1 | Sun, Sep 9 | Pittsburgh | W 31-19 |
| 2 | Mon, Sep 17 | at Atlanta | L 27-21 |
| 3 | Sun, Sep 23 | Houston | L 31-25 |
| 4 | Sun, Sep 30 | Oakland | W 37-6 |
| 5 | Sun, Oct 7 | at New England | L 31-21 |
| 6 | Mon, Oct 15 | at San Diego | W 35-24 |
| 7 | Sun, Oct 23 | BYE | |
| 8 | Sun, Oct 28 | New Orleans | W 34-14 |
| 9 | Sun, Nov 4 | at Cincinnati | W 31-23 |
| 10 | Sun, Nov 11 | at Carolina | W 36-14 |
| 11 | Sun, Nov 18 | San Diego | W 30-23 |
| 12 | Sun, Nov 25 | at Kansas City | W 17-9 |
| 13 | Sun, Dec 2 | Tampa Bay | W 31-23 |
| 14 | Thu, Dec 6 | at Oakland | W 26-13 |
| 15 | Sun, Dec 16 | at Baltimore | W 34-17 |
| 16 | Sun, Dec 23 | Cleveland | W 34-12 |
| 17 | Sun, Dec 30 | Kansas City | W 38-3 |
